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INFLAMMATORY PROTEINS, MACROPHAGE
Descriptors Found:
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DeCS
Descriptor
English
:
Macrophage Inflammatory Proteins
Descriptor
Spanish
:
Proteínas Inflamatorias de Macrófagos
Descriptor
Portuguese
:
Proteínas Inflamatórias de Macrófagos
Synonyms
English
:
Inflammatory Proteins, Macrophage
Macrophage Inflammatory Protein-1
Tree Number:
D12.644.276.374.200.600
D12.776.467.374.200.600
D23.125.300.600
D23.469.200.600
D23.529.374.200.600
Definition
English
:
Heparin-binding
proteins
that
exhibit
a number of inflammatory and immunoregulatory activities. Originally identified as secretory products of
MACROPHAGES
, these
chemokines
are produced by a variety of cell types including
NEUTROPHILS
;
FIBROBLASTS
; and
EPITHELIAL CELLS
. They likely play a significant role in respiratory tract defenses.
History Note
English
:
1997
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
33073
Unique Identifier:
D019402
Occurrence in VHL
:
Similar:
DeCS